Aging Interventions - Rapamycin, NAD+ & Dog Aging Project | Matt Kaeberlein
Live Longer World Podcast #5
Live Longer World Podcast Episode #5 has been released!
My guest is Dr. Matt Kaeberlein who is a Professor of Pathology, Adjunct Professor of Genome Sciences, and Adjunct Professor of Oral Health Sciences at the University of Washington.
His research interests are focused on basic mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life.
Matt has been around the field of aging for a long time and knows more about the work in the aging field than perhaps anyone else.
We discuss:
How Matt thinks of aging from a functional perspective
Caloric restriction and Aging
Whether NAD+ precursors are effective in slowing aging
The role of sirtuins in slowing aging
Quite a bit on Rapamycin and how it’s shown to be effective in improving the health of mice
Matt is very excited about the potential benefits of Rapamycin in reversing aging and he got me excited too.
Matt is also working on the Dog Aging project and in trying to understand aging in dogs
Finally, we end the conversation by talking a bit on what good scientific practices should look like
Matt approaches his work with an unbiased lens and that’s very respectable
Matt has a brilliant mind. We had such a comprehensive discussion on various aging interventions as I mentioned above. I had such a blast talking to Matt and I hope you enjoy the conversation as much as I did!
Listen to the Podcast:
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Apple Podcasts:
Podcast Website + Other Platforms: here
Sneak Peak on the Next Episode..🤫
The next episode is a very special guest who will tell you about a better new way of measuring your biological age! 😉
If you want to be notified of upcoming podcast releases, please make sure to subscribe!
In Case you missed my other Episodes:
Episode #4: Investing in Longevity, Regenerative Medicine, and Longevity Escape Velocity with Dave Gobel, the CEO of Methuselah Foundation
Episode #3: Skin Aging, Senolytics & Building a Longevity Company with Carolina Oliveira, the founder & CEO of OneSkin Technologies
Episode #2: Brain Aging, Tissue Cell Replacement, and Radical Strategy to Fight Aging with Dr. Jean Hebert, Professor of Neuroscience at Albert Einstein College of Medicine
Episode #1: How to Fight Aging, NAD+ Boosters, Senolytics & Curing Atherosclerosis with Reason, the Founder & CEO of Repair Biotechnologies
If you are learning from my work and finding it valuable, I’d love your support in sharing it with your friends & family!
I've also been interested in rapamycin and the studies that show that it can slow down aging. The lowering of mTOR with rapamycin created a benefit in brain health in a well run mouse experiment. I strongly believe that people in the know will be living much longer life spans going forward.
https://mattcook.substack.com/p/how-to-stop-and-slow-down-dementia
I'd be interested in Dr. Kaeberlein's thoughts about Nuchido Time+ and Dr. Conlon's work; check it out at nuchido.com